IMDb 5.8 2010 HD

Splice

Splice

2010
Horror Science Fiction
104 min R Canada
5.866 / 10
5.8 IMDB

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a…

Personnel // Cast & Crew

Director Vincenzo Natali / Lisa Burling / Sarah Campbell / Bob Munroe / Andrew Shea
Starring
Adrien Brody / Sarah Polley / Delphine Chanéac / David Hewlett / Abigail Chu / Stephanie Baird / Brandon McGibbon / Amanda Brugel

How Viewers Describe This Film

Common themes and sentiments

unsettling thought-provoking disturbing intelligent tense creepy ambitious complex fascinating cautionary visceral

Reviews

P
Penelope Hayes
Apr 29, 2026
3.5 / 5
3.5

This is not your typical monster movie. Splice offers a more cerebral and unsettling brand of horror, focusing on the psychological fallout of forbidden science. Adrien Brody and Sarah Polley are excellent as the scientists pushing the envelope,…

J
Julian Croft
Apr 29, 2026
4.5 / 5
4.5

Splice is a rare breed: a science fiction horror film that is as intellectually stimulating as it is viscerally disturbing. The performances from Brody and Polley are nuanced, portraying the seductive allure and ultimate horror of their creation.…

G
Genevieve Dubois
Apr 29, 2026
3.0 / 5
3.0

A visually arresting and conceptually daring film, Splice grapples with weighty themes of creation and consequence. Sarah Polley and Adrien Brody bring a compelling, if slightly detached, intensity to their roles as ambitious geneticists. The creature design for…

M
Marcus Thorne
Apr 29, 2026
4.0 / 5
4.0

Vincenzo Natali's Splice is a masterclass in intelligent creature feature filmmaking. It’s a film that respects its audience, eschewing easy answers for complex moral quandaries. Brody and Polley are perfectly cast, their descent into obsession feeling earned. The…

E
Eleanor Vance
Apr 29, 2026
3.5 / 5
3.5

Splice is a film that lingers, a disquieting exploration of scientific ambition gone awry. Adrien Brody and Sarah Polley deliver committed performances as the ethically flexible scientists, their desperation palpable. Delphine Chanéac is a revelation as Dren, transforming…

FAQs

Absolutely. Splice serves as a potent cautionary tale regarding the unchecked pursuit of scientific innovation, particularly in the field of genetic engineering. The film vividly illustrates the potential for unforeseen and catastrophic outcomes when ethical and legal boundaries are disregarded. It prompts viewers to consider the profound responsibilities that accompany such powerful scientific capabilities and the potential for humanity to unleash forces it cannot comprehend or control.