IMDb 4.8 2005 HD

Side Effects

Side Effects

2005
Comedy Drama Romance
90 min R USA
5.6 / 10
4.8 IMDB

America! Built on a better pill. Karly Hert has spent the last ten years selling drugs. Legally, that is. Karly is a pharmaceutical sales representative. She sells pills…

Personnel // Cast & Crew

Director Kathleen Slattery-Moschkau / Nicholas Owen Langholff / Liza Hanson / Peter J. Olsen / Steve Moschkau
Starring
Katherine Heigl / Lucian McAfee / David Durbin / Dorian DeMichele / Temeceka Harris / Beth Hebert / Mimi Sagadin / Sandy Adell

How Viewers Describe This Film

Common themes and sentiments

thought-provoking critical realistic unsettling corporate ethical dramatic insightful grounded cynical professional engaging

Reviews

C
Chloe Davies
May 6, 2026
3.5 / 5
3.5

Katherine Heigl delivers a compelling performance in 'Side Effects,' a film that offers a measured look at the machinations of the pharmaceutical sales world. The director's claimed insider knowledge lends the narrative a sense of verisimilitude, exploring the…

J
Julian Thorne
May 6, 2026
4.5 / 5
4.5

A bracingly intelligent film, 'Side Effects' succeeds through its grounded perspective and a commanding performance from Katherine Heigl. The director’s alleged decade within the pharmaceutical sector imbues the story with an undeniable authenticity. The film eschews easy answers,…

S
Sophia Chen
May 6, 2026
3.0 / 5
3.0

'Side Effects' presents a familiar, yet still potent, critique of the pharmaceutical industry, driven by Katherine Heigl’s capable portrayal of a seasoned sales rep. The film’s premise, rooted in the director’s industry background, lends it a degree of…

M
Marcus Bellweather
May 6, 2026
4.0 / 5
4.0

This is a sharp, insightful drama that uses Katherine Heigl's considerable talents to full effect. 'Side Effects' is less a thriller and more a character study steeped in the realities of the pharmaceutical world. The director, drawing from…

E
Eleanor Vance
May 6, 2026
3.5 / 5
3.5

Katherine Heigl anchors 'Side Effects' with a performance that captures the creeping cynicism of a pharmaceutical sales rep navigating a morally ambiguous landscape. The film, purportedly informed by the director's own industry tenure, offers a glimpse behind the…

FAQs

While the plot summary focuses on Karly's professional life and her growing unease about the pharmaceutical industry, the film's premise inherently suggests an exploration of the impact of medication. As a pharmaceutical sales representative, her role is to facilitate the use of drugs. The 'growing pit in Karly's stomach' hints at a potential reckoning with the consequences, both personal and societal, of the products she promotes.